Skin thickness affects the result of tuberculin skin test in systemic sclerosis.

ABSTRACT:

Background

Skin thickness is a prominent clinical feature of systemic sclerosis (SSc), but there is no consensus on the cut-off for a positive tuberculin skin test (TST) size and the limitation of the TST for a diagnosis of tuberculosis in SSc. We aimed to identify the cut-off size of an indurated TST and the sensitivity and specificity of the test for the diagnosis of tuberculosis in SSc patients.

Methods

A cross-sectional study of 168 adult Thai SSc patients was conducted. The TST was done using 0.1 ml of purified protein derivatives via intradermal injection. The test was interpreted 72 h after testing.

Results

The median age was 57.2 years. The majority (71.8%) had the diffuse cutaneous SSc subset. All the patients had a BCG vaccination at birth, and 17 (10.1%) ha

SUBMITTER: So-Ngern A 

PROVIDER: S-EPMC9375415 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature