Serum proteomics of severe fever with thrombocytopenia syndrome patients.

ABSTRACT:

Background

Dabie bandavirus, also termed as severe fever with thrombocytopenia syndrome virus (SFTSV), was first isolated in China in 2010. At this time, the virus was found to have spread to South Korea, Japan, and other countries. A high case fatality rate is reported for SFTS, ranging from 12-50% within various sources. Several omics for clinical studies among SFTS patients as well as studies of cultured SFTSV have attempted to characterize the relevant molecular biology and epidemiology of the disease. However, a global serum proteomics analysis among SFTS patients has not yet been reported to date.

Methods

In the current study, we evaluated comparative serum proteomics among SFTS patients (eight recovered patients and three deceased patients) with the goal of identifyin

SUBMITTER: Lee SY 

PROVIDER: S-EPMC9375430 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature