Prediction of Neurological Deterioration After Intracerebral Hemorrhage: The SIGNALS Score.

ABSTRACT: Background Intracerebral hemorrhage is the most disabling and lethal form of stroke. We aimed to develop a novel clinical score for neurological deterioration during hospitalization after intracerebral hemorrhage. Methods and Results We analyzed data from the CHERRY (Chinese Cerebral Hemorrhage: Mechanism and Intervention) study. Two-thirds of eligible patients were randomly allocated into the training cohort (n=1027) and one-third into the validation cohort (n=515). Multivariable logistic regression was used to identify factors associated with neurological deterioration (an increase in National Institutes of Health Stroke Scale of ≥4 or death) within 15 days after symptom onset. A prediction score was developed based on regression coefficients derived from the logistic model. The site, si

SUBMITTER: He Q 

PROVIDER: S-EPMC9375508 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature