Influenza infection is not associated with phenotypical frailty in older patients, a prospective cohort study.

ABSTRACT:

Background and aims

Influenza is a challenging infectious illness for older adults. It is not completely clear whether influenza is associated with frailty or functional decline. We sought to determine the association between incident influenza infection and frailty and prefrailty in community patients over 50 years of age. We also investigated the association between influenza vaccination and frailty and prefrailty as a secondary aim.

Methods

This was a prospective community cohort study from October 2019 to November 2020 in participants over 50 years. The primary outcome was the development of frailty as defined by three of five frailty criteria (slow gait speed, low grip strength, 5% weight loss, low energy, and low physical functioning). The primary predictor was a posit

SUBMITTER: Takahashi P 

PROVIDER: S-EPMC9376026 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature