The global inhomogeneity index assessed by electrical impedance tomography overestimates PEEP requirement in patients with ARDS: an observational study.

ABSTRACT:

Background

Electrical impedance tomography (EIT) visualises alveolar overdistension and alveolar collapse and enables optimisation of ventilator settings by using the best balance between alveolar overdistension and collapse (ODCL). Besides, the global inhomogeneity index (GI), measured by EIT, may also be of added value in determining PEEP. Optimal PEEP is often determined based on the best dynamic compliance without EIT at the bedside. This study aimed to assess the effect of a PEEP trial on ODCL, GI and dynamic compliance in patients with and without ARDS. Secondly, PEEP levels from "optimal PEEP" approaches by ODCL, GI and dynamic compliance are compared.

Methods

In 2015-2016, we included patients with ARDS using postoperative cardiothoracic surgery patients as a referen

SUBMITTER: Heines SJH 

PROVIDER: S-EPMC9377133 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature