Ontology highlight
ABSTRACT:
SUBMITTER: Hurni C
PROVIDER: S-EPMC9377612 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Hurni Clémence C Weger Benjamin D BD Gobet Cédric C Naef Felix F
PLoS genetics 20220803 8
In eukaryotes, RNA is synthesised in the nucleus, spliced, and exported to the cytoplasm where it is translated and finally degraded. Any of these steps could be subject to temporal regulation during the circadian cycle, resulting in daily fluctuations of RNA accumulation and affecting the distribution of transcripts in different subcellular compartments. Our study analysed the nuclear and cytoplasmic, poly(A) and total transcriptomes of mouse livers collected over the course of a day. These dat ...[more]