A feasibility study of low-dose ketamine for acute management of suicidal ideation.

ABSTRACT:

Objective

Mood disorders complicated by suicidal ideation (SI) frequently present to the emergency department (ED) for care. Currently, patients with SI in the ED do not typically receive targeted interventions. Ketamine may have a role in treating SI within the ED because subanesthetic doses have rapid-acting antidepressant and antisuicidal properties.

Methods

This single-arm, open-label feasibility study enrolled 14 participants from the ED with acute SI who were awaiting voluntary admission to inpatient psychiatry to receive ketamine at 0.5 mg/kg, administered intravenously. Participants were assessed post administration to evaluate feasibility of administration in the ED and short-term effectiveness. Feasibility was determined by acceptability by patients and physicians

SUBMITTER: Gaither R 

PROVIDER: S-EPMC9377682 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature