Analysis of the Influencing Factors of Immunological Nonresponders in Wuhan, China.

ABSTRACT:

Objective

CD4⁺ cell recovery is hampered in some human immunodeficiency virus (HIV)-infected patients, despite a successful highly active antiretroviral therapy (HAART) with suppressed viral replication. We investigated the factors that might have hindered the CD4⁺ cell recovery in these patients.

Methods

In this retrospective study, we collected the data of all immune nonresponders (INRs) in Wuhan, China, until the end of 2020. A linear model was constructed based on the data from 220 patients with baseline and follow-up records. The response variables in this study were the CD4⁺ cell count increase. The predictor variables considered in this study were those factors likely to affect the CD4⁺ cell recovery.

Results

Our find

SUBMITTER: Lei E 

PROVIDER: S-EPMC9377976 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature