Treatment success with two doses of methotrexate vs single dose of methotrexate in Ectopic Tubal Pregnancy.

ABSTRACT:

Objectives

To compare the success rates and safety of two-doses of methotrexate versus single dose of methotrexate in ectopic tubal pregnancy.

Methods

This was an open-label, randomized controlled trial done at "The Department of Obstetrics & Gynecology, Nishtar University Hospital, Multan" from January 2020 to July 2021. A total of 100 women (50 in each group), aged 20 to 35 years with a tubal ectopic pregnancy were enrolled. All patients were randomly allocated to either single-dose or two-dose methotrexate protocol. Cases were evaluated for treatment success, side effects, beta-human chorionic gonadotrophin (β-hCG) resolution time and treatment satisfaction.

Results

In a total of 100 cases, mean age was 29.6±4.5 years. Mean serum β -hCG levels at baseline was 1212±

SUBMITTER: Khakwani M 

PROVIDER: S-EPMC9378401 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature