Fish oil blunts lung function decrements induced by acute exposure to ozone in young healthy adults: A randomized trial.

ABSTRACT:

Background

Over one-third of the U.S. population is exposed to unsafe levels of ozone (O₃). Dietary supplementation with fish oil (FO) or olive oil (OO) has shown protection against other air pollutants. This study evaluates potential cardiopulmonary benefits of FO or OO supplementation against acute O₃ exposure in young healthy adults.

Methods

Forty-three participants (26 ± 4 years old; 47% female) were randomized to receive 3 g/day of FO, 3 g/day OO, or no supplementation (CTL) for 4 weeks prior to undergoing 2-hour exposures to filtered air and 300 ppb O₃ with intermittent exercise on two consecutive days. Outcome measurements included spirometry, sputum neutrophil percentage, blood markers of inflammation, tissue injury and coagulation, v

SUBMITTER: Chen H 

PROVIDER: S-EPMC9378480 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature