Quality of Life in Adolescents and Young Adults: The Role of Symptom Burden.

ABSTRACT:

Context

Adolescents and young adults (AYAs) with cancer report worse health-related quality of life (HRQOL) than other age groups. Symptom burden is a modifiable predictor of HRQOL.

Objectives

The objective of this study was to identify which symptoms are most burdensome to AYAs with advanced cancer.

Methods

In this observational study, English-speaking individuals aged 12-25 years undergoing treatment for advanced cancer completed assessments of symptom burden (Memorial Symptom Assessment Scale) and HRQOL (Pediatric Quality of Life Inventory Generic Form and Cancer Module; minimal clinically important difference 4.4). We dichotomized participants as having low (<7) or high (≥7) symptom prevalence. Mixed regression models estimated HRQOL differences between groups. Fo

SUBMITTER: Steineck A 

PROVIDER: S-EPMC9378571 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature