PM_2.5 air pollution exposure and nonalcoholic fatty liver disease in the Nationwide Inpatient Sample.

ABSTRACT:

Background

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. Particulate matter air pollution <2.5 μm in diameter (PM_2.5) is a ubiquitous exposure primarily produced from fossil fuel combustion. Previous epidemiologic studies have been mixed. The objective of this study was to examine the association between ambient PM_2.5 exposure and NAFLD among hospitalized patients in the Nationwide Inpatient Sample (NIS).

Methods

We conducted a cross-sectional analysis of hospitalizations from 2001 to 2011 using the NIS, the largest nationally representative all-payer inpatient care administrative database in the United States. Average annual PM_2.5 exposure was estimated by linking census tracts (based on NIS-prov

SUBMITTER: VoPham T 

PROVIDER: S-EPMC9378584 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature