Dataset Information

International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.

ABSTRACT:

Background & aims

Substantial heterogeneity in terminology used for eosinophilic gastrointestinal diseases (EGIDs), particularly the catchall term "eosinophilic gastroenteritis," limits clinical and research advances. We aimed to achieve an international consensus for standardized EGID nomenclature.

Methods

This consensus process utilized Delphi methodology. An initial naming framework was proposed and refined in iterative fashion, then assessed in a first round of Delphi voting. Results were discussed in 2 consensus meetings, and the framework was updated and reassessed in a second Delphi vote, with a 70% threshold set for agreement.

Results

Of 91 experts participating, 85 (93%) completed the first and 82 (90%) completed the second Delphi surveys. Consensus was reached on all but 2 statements. "EGID" was the preferred umbrella term for disorders of gastrointestinal (GI) tract eosinophilic inflammation in the absence of secondary causes (100% agreement). Involved GI tract segments will be named specifically and use an "Eo" abbreviation convention: eosinophilic gastritis (now abbreviated EoG), eosinophilic enteritis (EoN), and eosinophilic colitis (EoC). The term "eosinophilic gastroenteritis" is no longer preferred as the overall name (96% agreement). When >2 GI tract areas are involved, the name should reflect all of the involved areas.

Conclusions

This international process resulted in consensus for updated EGID nomenclature for both clinical and research use. EGID will be the umbrella term, rather than "eosinophilic gastroenteritis," and specific naming conventions by location of GI tract involvement are recommended. As more data are developed, this framework can be updated to reflect best practices and the underlying science.

SUBMITTER: Dellon ES

PROVIDER: S-EPMC9378753 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Publications

International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.

Dellon Evan S ES Gonsalves Nirmala N Abonia J Pablo JP Alexander Jeffrey A JA Arva Nicoleta C NC Atkins Dan D Attwood Stephen E SE Auth Marcus K H MKH Bailey Dominique D DD Biederman Luc L Blanchard Carine C Bonis Peter A PA Bose Paroma P Bredenoord Albert J AJ Chang Joy W JW Chehade Mirna M Collins Margaret H MH Di Lorenzo Carlo C Dias Jorge Amil JA Dohil Ranjan R Dupont Christophe C Falk Gary W GW Ferreira Cristina T CT Fox Adam T AT Genta Robert M RM Greuter Thomas T Gupta Sandeep K SK Hirano Ikuo I Hiremath Girish S GS Horsley-Silva Jennifer L JL Ishihara Shunji S Ishimura Norihisa N Jensen Elizabeth T ET Gutiérrez-Junquera Carolina C Katzka David A DA Khoury Paneez P Kinoshita Yoshikazu Y Kliewer Kara L KL Koletzko Sibylle S Leung John J Liacouras Chris A CA Lucendo Alfredo J AJ Martin Lisa J LJ McGowan Emily C EC Menard-Katcher Calies C Metz David C DC Miller Talya L TL Moawad Fouad J FJ Muir Amanda B AB Mukkada Vincent A VA Murch Simon S Nhu Quan M QM Nomura Ichiro I Nurko Samuel S Ohtsuka Yoshikazu Y Oliva Salvatore S Orel Rok R Papadopoulou Alexandra A Patel Dhyanesh A DA Pesek Robert D RD Peterson Kathryn A KA Philpott Hamish H Putnam Philip E PE Richter Joel E JE Rosen Rachel R Ruffner Melanie A MA Safroneeva Ekaterina E Schreiner Philipp P Schoepfer Alain A Schroeder Shauna R SR Shah Neil N Souza Rhonda F RF Spechler Stuart J SJ Spergel Jonathan M JM Straumann Alex A Talley Nicholas J NJ Thapar Nikhil N Vandenplas Yvan Y Venkatesh Rajitha D RD Vieira Mario C MC von Arnim Ulrike U Walker Marjorie M MM Wechsler Joshua B JB Wershil Barry K BK Wright Benjamin L BL Yamada Yoshiyuki Y Yang Guang-Yu GY Zevit Noam N Rothenberg Marc E ME Furuta Glenn T GT Aceves Seema S SS

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20220216 11

<h4>Background & aims</h4>Substantial heterogeneity in terminology used for eosinophilic gastrointestinal diseases (EGIDs), particularly the catchall term "eosinophilic gastroenteritis," limits clinical and research advances. We aimed to achieve an international consensus for standardized EGID nomenclature.<h4>Methods</h4>This consensus process utilized Delphi methodology. An initial naming framework was proposed and refined in iterative fashion, then assessed in a first round of Delphi voting. ...[more]

PMID: 35181570

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Dataset Information

International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.

Background & aims

Methods

Results

Conclusions

Publications

International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature.

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