The characteristics of arterial spin labeling cerebral blood flow in patients with subjective cognitive decline: The Chinese imaging, biomarkers, and lifestyle study.

ABSTRACT:

Objective

We aimed to characterize the potential risk factors and cerebral perfusion of patients with subjective cognitive decline (SCD).

Methods

This prospective study enrolled consecutive patients from the Chinese Imaging, Biomarkers, and Lifestyle (CIBL) Cohort of Alzheimer's disease between February 2021 and March 2022. Patients who met the SCD diagnostic criteria were categorized into the SCD group, while those without cognitive complaints or any concerns were assigned to the healthy control (HC) group. The demographic and clinical characteristics and cerebral blood flow (CBF) from pseudo-continuous arterial spin labeling (pCASL) in standard cognitive regions were compared between these two groups. A multivariate analysis was performed to identify independent factors as

SUBMITTER: Li W 

PROVIDER: S-EPMC9379247 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature