Choriocapillaris Flow Imbalance in Fellow Eyes in Age-Related Macular Degeneration.

ABSTRACT:

Purpose

The purpose of this study was to identify early changes in choriocapillaris flow in patients with age-related macular degeneration (AMD) with no history of macular neovascularization (MNV).

Methods

Clinical records of fellow eyes of patients with unilateral neovascular AMD without fundus findings and control eyes of otherwise healthy individuals, except for mild cataract, diagnosed at St. Luke's International Hospital from April 2020 to March 2021, were retrospectively analyzed. Optical coherence tomography (OCT) angiography images of the choriocapillaris slab were binarized using the Phansalkar local thresholding methods to evaluate the choriocapillaris flow area (CCFA) and its coefficient of variation (CV).

Results

The data of 24 AMD fellow eyes (17 for men,

SUBMITTER: Harada N 

PROVIDER: S-EPMC9379328 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature