Emergence of plasmid-mediated tigecycline, β-lactam and florfenicol resistance genes tet(X), bla_OXA-347 and floR in Riemerella anatipestifer isolated in China.

ABSTRACT: Bacterial antimicrobial resistance (AMR) continues to develop, with the horizontal transfer of antibiotic resistance genes (ARGs) through plasmids playing a major role. Recently, the antimicrobial resistance of R. anatipestifer has become increasingly severe, jeopardizing the development of the poultry industry. In this study, we used PromethION to determine the whole genome sequence of R. anatipestifer RCAD0416, a multidrug-resistant isolate from China. We detected a plasmid in the isolate. We named the plasmid pRCAD0416RA-1; the plasmid was 37356 bp in size with 36 putative open reading frames and included the bla_OXA-347, floR, tet(X), ermF, ereD, and AadS resistance genes. Most resistance genes might be obtained from R. anatipestifer HXb2. Mobile elements and floR might be tr

SUBMITTER: Zhu D 

PROVIDER: S-EPMC9379664 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature