Association of Corpus Callosum Development With Fetal Growth Restriction and Maternal Preeclampsia or Gestational Hypertension.

ABSTRACT:

Importance

It remains unknown whether neurodevelopmental impairments are directly associated with the structural development of the brain in offspring with fetal growth restriction (FGR) and mothers with preeclampsia (PE) or gestational hypertension (GH).

Objectives

To assess whether fetal corpus callosum (CC) development differed among pregnancies with PE or GH with FGR, pregnancies with PE or GH without FGR, and normotensive pregnancies, particularly the severity of maternal disease and FGR, and to identify the association between adverse perinatal outcomes and structural development of the CC in fetuses with FGR in pregnancies with PE or GH.

Design, setting, and participants

This retrospective matched case-control study was conducted between January 1, 2014, and Ja

SUBMITTER: Zheng W 

PROVIDER: S-EPMC9379741 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature