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Persistent aura and status migrainosus in CADASIL syndrome: A case report.

ABSTRACT: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy characterized by a genetic predisposition to small arteries of the brain. It is produced by a mutation in the NOTCH3 gene and concerns adults. The symptomatology is diversified including migraines with or without aura, subcortical ischemic events, and cognitive impairment. The diagnosis of CADASIL is suspected by neuroimaging and confirmed by genetic testing. Treatment of the disease remains preventive. We report a case of CADASIL manifesting as status migrainosus with persistent aura.

SUBMITTER: Hamid M

PROVIDER: S-EPMC9379942 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Persistent aura and status migrainosus in CADASIL syndrome: A case report.

Hamid Mohamed M Adraoui Yassine El YE Satte Amal A Bourazza Ahmed A

Radiology case reports 20220810 10

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary microangiopathy characterized by a genetic predisposition to small arteries of the brain. It is produced by a mutation in the NOTCH3 gene and concerns adults. The symptomatology is diversified including migraines with or without aura, subcortical ischemic events, and cognitive impairment. The diagnosis of CADASIL is suspected by neuroimaging and confirmed by genetic testing. Treat ...[more]

PMID: 35982717

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