Mapping the genetic and environmental aetiology of autistic traits in Sweden and the United Kingdom.

ABSTRACT:

Background

Autistic traits are influenced by both genetic and environmental factors, and are known to vary geographically in prevalence. But to what extent does their aetiology also vary from place to place?

Methods

We applied a novel spatial approach to data on autistic traits from two large twin studies, the Child and Adolescent Twin Study in Sweden (CATSS; N = 16,677, including 8307 twin pairs) and the Twins Early Development Study in the UK (TEDS; N = 11,594, including 5796 twin pairs), to explore how the influence of nature and nurture on autistic traits varies from place to place.

Results

We present maps of gene- and environment- by geography interactions in Sweden and the United Kingdom (UK), showing geographical variation in both genetic and envi

SUBMITTER: Reed ZE 

PROVIDER: S-EPMC9379966 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature