Serum adiponectin-levels are predictive of probable posttraumatic stress disorder in women.

ABSTRACT:

Background

Accumulative evidence indicates a role for adiponectin, a polypeptide secreted by adipose tissue, in the pathophysiology of posttraumatic disorder (PTSD) via metabolic and inflammatory pathways. This study examined adiponectin as a potential predictive biomarker for PTSD among female rape survivors.

Methods

We evaluated the relationship of baseline serum adiponectin levels to the development of probable PTSD at 3- and 6-months post rape-exposure and compared adiponectin levels between 542 rape-exposed (RE) and 593 rape-unexposed women (RUE). Probable PTSD were defined as Davidson Trauma Scale score ≥40. Data were analysed using multivariate regression models and a generalized estimating equation (GEE) model. We adjusted for clinically relevant covariates associate

SUBMITTER: Vuong E 

PROVIDER: S-EPMC9379978 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature