Warming up for a better fever: a randomized pilot study in pediatric oncology.

ABSTRACT:

Background

Fever in children is a major problem in pediatric oncology. Usual management leads to immediate antibiotic and antipyretic therapy, although there is consensus that antipyretic therapy should not be utilized with the sole aim of reducing body temperature. Increased body temperature during fever appears to be an effective modifier in terms of viral replication and enhanced host defense mechanisms against pathogens. Therefore, it might be beneficial to support febrile patients by applying gentle heat during the onset of fever to help the body to reach its new thermoregulatory set point.

Methods

A randomized pilot study over 6 months will be conducted in a pediatric oncology department in an academic hospital in Germany. This study is a preparation for a multicenter

SUBMITTER: Krafft HS 

PROVIDER: S-EPMC9380316 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature