Association of maternal HDL2-c concentration in the first trimester and the risk of large for gestational age birth.

ABSTRACT:

Background

Maternal lipid levels during pregnancy are critical for fetal development. Recent studies revealed that high-density lipoprotein cholesterol (HDL-c) levels during pregnancy were negatively correlated with birthweight. High-density lipoprotein 2 cholesterol (HDL2-c) is one of the major subclasses of HDL-c, and its relationship with birthweight is unclear. Association of HDL2-c concentration in the first trimester and risk of large for gestational age (LGA) was explored.

Methods

This study recruited pregnant women who registered in Fuxing Hospital from October 2018 to January 2020, had regular obstetric examinations during pregnancy, and delivered between June 2019 and September 2020. Finally, 549 participants were recruited for the study. Maternal demographic chara

SUBMITTER: Huang D 

PROVIDER: S-EPMC9380360 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature