Establishment of an early diagnosis model of colon cancerous bowel obstruction based on 1H NMR.

ABSTRACT:

Objective

To prospectively establish an early diagnosis model of acute colon cancerous bowel obstruction by applying nuclear magnetic resonance hydrogen spectroscopy(1H NMR) technology based metabolomics methods, combined with machine learning.

Methods

In this study, serum samples of 71 patients with acute bowel obstruction requiring emergency surgery who were admitted to the Emergency Department of Sichuan Provincial People's Hospital from December 2018 to November 2020 were collected within 2 hours after admission, and NMR spectroscopy data was taken after pretreatment. After postoperative pathological confirmation, they were divided into colon cancerous bowel obstruction (CBO) group and adhesive bowel obstruction (ABO) control group. Used MestReNova software to extract th

SUBMITTER: Zeng J 

PROVIDER: S-EPMC9380946 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature