Clonal dissemination of carbapenem-resistant Klebsiella pneumoniae ST16 co-producing NDM-1 and OXA-232 in Thailand.

ABSTRACT:

Background

Klebsiella pneumoniae ST258 and ST11 carrying bla _KPC are among the most widespread carbapenem-resistant K. pneumoniae strains worldwide. Our carbapenem-resistant Enterobacteriaceae surveillance in Thailand revealed a nationwide dissemination of K. pneumoniae ST16 isolates carrying bla _NDM-1 and bla _OXA-232.

Objectives

To analyse the genomic details of this nationwide dissemination by focusing on plasmids and virulence factors.

Methods

Using WGS data of 119 K. pneumoniae ST16 isolates carrying bla _NDM-1 obtained in our previous surveillance study, clonality of chromosomes and plasmids of the isolates with carriage of virulence factors was evaluated.

Result

SUBMITTER: Abe R 

PROVIDER: S-EPMC9380991 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature