A systematic review on neutrophils interactions with titanium and zirconia surfaces: Evidence from in vitro studies.

ABSTRACT:

Objectives

This systematic review aimed to assess in vitro studies that evaluated neutrophil interactions with different roughness levels in titanium and zirconia implant surfaces.

Material and methods

An electronic search for literature was conducted on PubMed, Embase, Scopus, and Web of Science and a total of 14 studies were included. Neutrophil responses were assessed based on adhesion, cell number, surface coverage, cell structure, cytokine secretion, reactive oxygen species (ROS) production, neutrophil activation, receptor expression, and neutrophil extracellular traps (NETs) release. The method of assessing the risk of bias was done using the toxicological data reliability assessment tool (TOXRTOOL).

Results

Ten studies have identified a significant increase in

SUBMITTER: Elangovan G 

PROVIDER: S-EPMC9382042 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature