Patients with diffuse idiopathic skeletal hyperostosis have an increased burden of thoracic aortic calcifications.

ABSTRACT:

Objectives

DISH has been associated with increased coronary artery calcifications and incident ischaemic stroke. The formation of bone along the spine may share pathways with calcium deposition in the aorta. We hypothesized that patients with DISH have increased vascular calcifications. Therefore we aimed to investigate the presence and extent of DISH in relation to thoracic aortic calcification (TAC) severity.

Methods

This cross-sectional study included 4703 patients from the Second Manifestation of ARTerial disease cohort, consisting of patients with cardiovascular events or risk factors for cardiovascular disease. Chest radiographs were scored for DISH using the Resnick criteria. Different severities of TAC were scored arbitrarily from no TAC to mild, moderate or severe T

SUBMITTER: Harlianto NI 

PROVIDER: S-EPMC9382268 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature