Effects of ambient temperatures between 5 and 35 °C on energy balance, body mass and body composition in mice.

ABSTRACT:

Background

Considerable attention is currently focused on the potential to switch on brown adipose tissue (BAT), or promote browning of white adipose tissue, to elevate energy expenditure and thereby reduce obesity levels. These processes are already known to be switched on by cold exposure. Yet humans living in colder regions do not show lower levels of obesity. This could be because humans shield themselves from external temperatures, or because the resultant changes in BAT and thermogenesis are offset by elevated food intake, or reductions in other components of expenditure.

Scope of review

We exposed mice to 11 different ambient temperatures between 5 and 35 °C and characterized their energy balance and body weight/composition. As it got colder mice progressively increas

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC9382332 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature