Retinal Microvasculature and Choriocapillaris Flow Deficit in Relation to Serum Uric Acid Using Swept-Source Optical Coherence Tomography Angiography.

ABSTRACT:

Purpose

To explore the relationship between serum uric acid (SUA) and retinochoroidal microcirculation in the Chinese population.

Methods

This prospective cross-sectional study was conducted among the residents of Guangzhou, southern China. A commercially available optical coherence tomography angiography (OCTA) device was used to obtain the superficial vessel density (SVD) and deep vessel density in the retina and the choriocapillaris flow deficit (CFD) in the macular region. Univariable and multivariable linear regression models were used to assess the association of hyperuricemia and SUA levels with OCTA parameters.

Results

A total of 638 participants with normal SUA and 296 participants with hyperuricemia were included in the study. Parafoveal SVD was significantl

SUBMITTER: Lu Y 

PROVIDER: S-EPMC9382346 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature