The Relationship Between Prior Cancer Diagnosis and All-Cause Dementia Progression Among US Adults.

ABSTRACT:

Background

Cancer-related cognitive impairment (CRCI), a frequent effect of cancer and its treatments, shares common cognitive symptoms with dementia syndromes. Cross-sectional studies demonstrate an inverse relationship between cancer and dementia. However, the longitudinal relationship between dementia decline and cancer has not been investigated.

Objective

To evaluate the association between cancer and longitudinal progression of dementia.

Methods

We extracted electronic health record data from July 2003 to February 2020 from a single academic medical center. We identified dementia and cancer history prior to dementia using ICD-9/10 codes. We measured cognitive decline with the Alabama Brief Cognitive Screener (ABCs). We used adjusted linear mixed models to estimat

SUBMITTER: Fowler ME 

PROVIDER: S-EPMC9382674 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature