Neutrophil-to-lymphocyte ratio is a predictive marker for anti-MDA5 positive dermatomyositis.

ABSTRACT:

Background

NLR is a systemic inflammatory marker that have been associated with overall survival in patients with some rapidly progressive disease. There are few data about the diagnostic and predictive value of NLR in autoimmune diseases, and it has not been described in anti-MDA5 positive DM. We try to correlate neutrophil-to-lymphocyte ratio (NLR) with fatality from dermatomyositis in anti-MDA5 positive patients.

Method

A retrospective study in which 195 patients were enrolled was conducted. Clinical and laboratory information was collated and ratios of neutrophil to lymphocyte counts (NLR) calculated. The primary end point was all-cause death.

Result

Of the 195 patients studied, all had interstitial lung disease, including 140 survivors and 55 non-survivors. An op

SUBMITTER: Liu T 

PROVIDER: S-EPMC9382756 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature