A survey of patients with laryngotracheal stenosis on future clinical trial design.

ABSTRACT:

Background/aims

Laryngotracheal stenosis is a rare but devastating proximal airway fibrosis that restricts a patient's ability to breathe. Treatment is primarily surgical and to date, there has never been a multi-institutional, randomized, prospective, and interventional clinical trial for a medical therapy to treat laryngotracheal stenosis. Therefore, we aimed to obtain patient feedback to guide successful trial design, recruitment, retention, and for identifying potential barriers to study participation.

Methods

Over 1000 members of an international laryngotracheal stenosis online support community (the Living with Idiopathic Subglottic Stenosis Facebook group) were sent two questionnaires for a proposed interventional double-blinded, randomized, placebo-controlled clinica

SUBMITTER: Lina I 

PROVIDER: S-EPMC9382824 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature