Effects of cardiopulmonary bypass on immunoglobulin G antibody titres after SARS-CoV2 vaccination.

ABSTRACT:

Objectives

Patients with cardiovascular disease are vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection. Although SARS-CoV2 vaccination may be effective, its impact on surgical patients is not well studied. We investigated the effects of cardiovascular surgery, especially under cardiopulmonary bypass (CPB), on the antibody titres after SARS-CoV2 vaccination.

Methods

A prospective observational study was designed for patients undergoing surgery between July and November 2021. The immunoglobulin G against the receptor-binding domain was measured and antibody preserved rate (APR) was calculated from perioperative titres comparison.

Results

Enrolled 63 study patients were divided into 39 undergoing surgery with CPB (Group CPB) and 24 withou

SUBMITTER: Hayashi R 

PROVIDER: S-EPMC9383986 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature