Epidemiological, virological and serological investigation of a SARS-CoV-2 outbreak (Alpha variant) in a primary school: A prospective longitudinal study.

ABSTRACT:

Objectives

To report a prospective epidemiological, virological and serological investigation of a SARS-CoV-2 outbreak in a primary school.

Methods

As part of a longitudinal, prospective, school-based surveillance study, this investigation involved repeated testing of 73 pupils, 9 teachers, 13 non-teaching staff and 26 household members of participants who tested positive, with rapid antigen tests and/or RT-PCR (Day 0-2 and Day 5-7), serologies on dried capillary blood samples (Day 0-2 and Day 30), contact tracing interviews and SARS-CoV-2 whole genome sequencing.

Results

We identified 20 children (aged 4 to 6 years from 4 school classes), 2 teachers and a total of 4 household members who were infected by the Alpha variant during this outbreak. Infection attack rates

SUBMITTER: Lorthe E 

PROVIDER: S-EPMC9385020 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature