Clinical use of the mRNA urinary biomarker SelectMDx test for prostate cancer.

ABSTRACT:

Background

Molecular biomarker tests are developed as diagnostic tools for prostate cancer (PCa) diagnosis. The SelectMDx (MDxHealth, Nijmegen, The Netherlands) test is a urinary-based biomarker test intended to be used to predict presence of high-grade PCa upon biopsy in men with elevated serum prostate-specific antigen (PSA) levels. Previous validation of the SelectMDx test revealed that 53% of the unnecessary biopsies (biopsies indicating no- or GG1 PCa) could be avoided using the SelectMDx test as a decision-tool to select men for prostate biopsy. The objective of this study is to examine the use of the commercially available SelectMDx test under routine, real-life practice.

Methods

Men that underwent a SelectMDx test between May 2019 and December 2020 and that were orig

SUBMITTER: Visser WCH 

PROVIDER: S-EPMC9385481 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature