PROMISE: a real-world clinical-genomic database to address knowledge gaps in prostate cancer.

ABSTRACT:

Purpose

Prostate cancer is a heterogeneous disease with variable clinical outcomes. Despite numerous recent approvals of novel therapies, castration-resistant prostate cancer remains lethal. A "real-world" clinical-genomic database is urgently needed to enhance our characterization of advanced prostate cancer and further enable precision oncology.

Methods

The Prostate Cancer Precision Medicine Multi-Institutional Collaborative Effort (PROMISE) is a consortium whose aims are to establish a repository of de-identified clinical and genomic patient data that are linked to patient outcomes. The consortium structure includes a (1) bio-informatics committee to standardize genomic data and provide quality control, (2) biostatistics committee to independently perform statistical anal

SUBMITTER: Koshkin VS 

PROVIDER: S-EPMC9385488 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature