Incipient chronic traumatic encephalopathy in active American football players: neuropsychological assessment and brain perfusion measures.

ABSTRACT:

Background and aims

Chronic traumatic encephalopathy (CTE) is a degenerative disease caused by repetitive traumatic brain injury (TBI). Because CTE can be definitely diagnosed only post-mortem, it would be important to explore clinical and radiological correlates of CTE and TBI. The aims of this study were to assess (1) the relationship between the neuropsychological profile of active American football players and the traumatic load; (2) whether traumatic brain injury associated with American football activity has a specific cerebral perfusion pattern; and (3) whether this perfusion pattern correlates with neuropsychological performances.

Methods

In 20 American football players [median age [25th-75th percentile] 25.0 [21.6-31.2] years, all males], we evaluated history, traum

SUBMITTER: Querzola G 

PROVIDER: S-EPMC9385804 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature