Point-of-care system for rapid real-time detection of SARS-CoV-2 virus based on commercially available Arduino platforms.

ABSTRACT: The COVID-19 pandemic emphasized the importance of rapid, portable, and on-site testing technologies necessary for resource-limited settings for effective testing and screening to reduce spreading of the infection. Realizing this, we developed a fluorescence-based point-of-care (fPOC) detection system with real-time reverse transcriptase loop-mediated isothermal amplification for rapid and quantitative detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The system is built based on the Arduino platform compatible with commercially available open-source hardware-software and off-the-shelf electronic components. The fPOC system comprises of three main components: 1) an instrument with integrated heaters, 2) optical detection components, and 3) an injection-mo

SUBMITTER: Van Ngoc H 

PROVIDER: S-EPMC9385952 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature