The association of long-term blood pressure variability with hemodialysis access thrombosis.

ABSTRACT:

Background

Blood pressure variability (BPV) is an important risk factor for cardiovascular events in hemodialysis patients. We sought to determine the impact of BPV on hemodialysis access thrombosis.

Methods

We enrolled 1,011 prevalent hemodialysis patients from 12 hemodialysis centers since January 2018 and followed them until December 2020. Predialysis blood pressure (BP) was assessed at 12-week intervals. The coefficient of variation derived from 36 consecutive BP measurements was used as the metric for variability. The primary outcome was incident hemodialysis access thrombosis. Linear regression models were used to assess factors associated with BPV at baseline. Kaplan-Meier curves of the time until vascular access events were drawn and log-rank tests were calculated. C

SUBMITTER: Hsieh MY 

PROVIDER: S-EPMC9386040 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature