Development of an indirect ELISA to detect PEDV specific IgA antibody based on a PEDV epidemic strain.

ABSTRACT:

Background

Porcine epidemic diarrhea (PED), a swine epidemic disease caused by porcine epidemic diarrhea virus (PEDV), is characterized by severe watery diarrhea, vomiting, dehydration and high mortality in piglets, and has caused serious economic losses to the global porcine industry. The level of PEDV IgA antibody is a key marker to assess the extent of passive immunity of the resistance against PEDV infection. However, current commercial structure proteins-based kits for detection of PEDV antibody are not affordable, and those kits require complicated antigen preparation procedures, which cannot meet the scope of economic benefits of many large-scale pig companies in China. Therefore, there is an urgent need to develop an accurate, simple, and economical method for IgA detection

SUBMITTER: Wang K 

PROVIDER: S-EPMC9386190 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature