Diversity of clonal complex 22 methicillin-resistant Staphylococcus aureus isolates in Kuwait hospitals.

ABSTRACT: CC22-MRSA is a major MRSA lineage that is widely reported globally. To characterize CC22-MRSA for trends in antibiotic resistance and emergence of variants, a total of 636 CC22 isolates identified by DNA microarray in 2016 (n = 195), 2017 (n = 227) and 2018 (n = 214) were investigated further using staphylococcal protein A (spa) typing and multilocus sequence typing. The isolates belonged to 109 spa types dominated by t223 (n = 160), t032 (n = 60), t852 (n = 59), t005 (n = 56) and t309 (n = 30) and 10 sequence types (STs) dominated by ST22 (85.5%). Genotypes CC22-MRSA-IV [tst1⁺]; CC22-MRSA-IV UK-EMRSA-15/Barnim EMRSA variants, CC22-MRSA-IV [PVL⁺], CC22-MRSA-IV [tst1⁺/PVL⁺] and

SUBMITTER: Boswihi SS 

PROVIDER: S-EPMC9386227 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature