Do individual psychological characteristics predict induction and generalization of nocebo and placebo effects on pain and itch?

ABSTRACT:

Background

Nocebo and placebo effects, i.e., adverse or beneficial treatment effects, respectively, putatively due to expectancies can modulate pain and itch. These effects can generalize within the pain or itch modality. Predicting the induction and generalization of these effects can be helpful in clinical practice. This study aims to investigate whether psychological characteristics related to the fear-avoidance model predict the induction and generalization of nocebo and placebo effects on pain and itch in young healthy participants.

Methods

Data from two previous experiments were analyzed. In Experiment 1, we induced nocebo and placebo effects on heat pain and tested generalization to pressure pain and to cowhage-evoked itch (n = 33 in a nocebo group, n =

SUBMITTER: Weng L 

PROVIDER: S-EPMC9386339 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature