Development and Validation of Models to Predict Poor Health-Related Quality of Life Among Adult Survivors of Childhood Cancer.

ABSTRACT:

Importance

Risk prediction models are important to identify survivors of childhood cancer who are at risk of experiencing poor health-related quality of life (HRQOL) as they age.

Objective

To develop and validate prediction models for a decline in HRQOL among adult survivors of childhood cancer.

Designs, setting, and participants

This prognostic study included 4755 adults from the Childhood Cancer Survivor Study (CCSS) diagnosed between January 5, 1970, and December 31, 1986, who completed baseline (time 0 [November 3, 1992, to August 28, 2003]) and 2 follow-up (time 1 [February 12, 2002, to May 21, 2005] and time 2 [January 6, 2014, to November 30, 2016]) surveys. Data were analyzed from June 19, 2019, to February 2, 2022.

Exposures

Sociodemographic, lifestyle

SUBMITTER: Schulte F 

PROVIDER: S-EPMC9386537 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature