Use of Saponinosomes from Ziziphus spina-christi as Anticancer Drug Carriers.

ABSTRACT: Saponins are plant glycosides with different structures and biological activities, such as anticancer effects. Ziziphus spina-christi is a plant rich in saponin, and this compound is used to treat malignant melanoma in the present study. Nanophytosomes can be used as an advantageous nanodrug delivery system for plant extracts. The aim of this work is to use the saponin-rich fraction (SRF) from Z. spina-christi and prepare SRF-loaded nanophytosomes (saponinosomes) and observe the in vitro and in vivo effects of these carriers. First, the SRF was obtained from Z. spina-christi by a solvent-solvent fractionation method. Then, Fourier transform infrared (FTIR) analyses were performed to confirm the presence of saponins in the extracted material. Subsequently, the saponinos

SUBMITTER: Nazemoroaya Z 

PROVIDER: S-EPMC9386697 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature