Comparison of 3 Different AMH Assays With AMH Levels and Follicle Count in Women With Polycystic Ovary Syndrome.

ABSTRACT:

Context

Anti-Müllerian hormone (AMH) levels strongly correlate with the number of antral follicles (total follicle count, TFC) in the ovary. In women with polycystic ovary syndrome (PCOS), this is reflected by significantly increased serum AMH levels. Different assays have been developed to measure AMH. However, little is known about the interassay correlation in women with increased AMH levels.

Objective

To investigate the correlation of AMH values between different AMH assays and with TFC in PCOS patients.

Methods

AMH levels were measured in 1660 PCOS patients, using 3 different AMH assays: Gen II (Beckman Coulter); picoAMH (Ansh Labs); and Elecsys (Roche). Passing Bablok regression was used to compare assay methods. Spearman's correlation was used to correlate AMH

SUBMITTER: Moolhuijsen LME 

PROVIDER: S-EPMC9387710 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature