Neurosyphilis presenting as autoimmune limbic encephalitis: A case report and literature review.

ABSTRACT:

Rationale

Neurosyphilis presenting as limbic encephalitis (LE) is an important differential diagnosis of autoimmune LE (ALE) defined by Graus in 2016. However, data on the clinical differences and similarities between neurosyphilis presenting as LE and ALE are limited. Herein, we report neurosyphilis presenting as ALE that fulfilled the main items of the Graus ALE criteria. Moreover, a literature review of neurosyphilis presenting as LE was performed.

Patient concerns

A 66-year-old Japanese man developed nonconvulsive status epilepticus. He presented with progressive personality change and working memory deficits within 3 months prior to admission. A hyperintense lesion localized in the bilateral medial temporal area was observed on T2-weighted fluid-attenuated inversion rec

SUBMITTER: Mizoguchi T 

PROVIDER: S-EPMC9388039 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature