Mapping developmental regionalization and patterns of cortical surface area from 29 post-menstrual weeks to 2 years of age.

ABSTRACT: Surface area of the human cerebral cortex expands extremely dynamically and regionally heterogeneously from the third trimester of pregnancy to 2 y of age, reflecting the spatial heterogeneity of the underlying microstructural and functional development of the cerebral cortex. However, little is known about the developmental patterns and regionalization of cortical surface area during this critical stage, due to the lack of high-quality imaging data and accurate computational tools for pediatric brain MRI data. To fill this critical knowledge gap, by leveraging 1,037 high-quality MRI scans with the age between 29 post-menstrual weeks and 24 mo from 735 pediatric subjects in two complementary datasets, i.e., the Baby Connectome Project (BCP) and the developing Human Connectome Project (dHCP

SUBMITTER: Huang Y 

PROVIDER: S-EPMC9388141 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature