Safety of inactivated SARS-CoV-2 vaccines in myasthenia gravis: A survey-based study.

ABSTRACT:

Background

Vaccination remains the most effective measure to prevent SARS-CoV-2 infection and worse outcomes. However, many myasthenia gravis (MG) patients are hesitant to receive vaccine due to fear of worsening.

Methods

MG patients were consecutively enrolled in two MG centers in North China. The "worsening" after vaccination was self-reported by MG patients, and severity was measured with a single simple question. The general characteristics and disease status immediately prior to the first dose were compared between the worsening and non-worsening groups. Independent factors associated with worsening were explored with multivariate regression analysis.

Results

One hundred and seven patients were included. Eleven patients (10.3%) reported worsening after vaccinatio

SUBMITTER: Li HY 

PROVIDER: S-EPMC9388926 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature