Tuberculosis dissemination in kidney transplant recipient treated with anti-CD40 monoclonal antibody: a case report.

ABSTRACT:

Background

Tuberculosis (TBC) in solid organ transplant recipients represents a severe complication. The incidence among transplant recipients is higher than in the general population, and the diagnosis and treatment remain challenging. We present a case of active disseminated tuberculosis in a kidney transplant recipient treated with an anti-CD40 monoclonal antibody, who had been previously exposed to an active form of the disease, but latent tuberculosis (LTBI) was repeatedly ruled out prior to transplantation. To the best of our knowledge, no other case has been reported in a patient treated with the anti-CD40 monoclonal antibody.

Case presentation

A 49-year-old patient, 1.5 years after primary kidney transplantation, presented with vocal cord problems, a dry irritating c

SUBMITTER: Bednarova K 

PROVIDER: S-EPMC9388963 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature