How do cardiovascular risk factors correlate with post-stroke cognitive function: Directly or indirectly through stroke severity?

ABSTRACT:

Objectives

Cognitive impairment may affect one-third of stroke survivors. Cardiovascular risk factors and stroke severity were known to be associated with cognitive function after stroke. However, it is unclear whether cardiovascular risk factors directly affect cognition after stroke, indirectly affect cognition by changing stroke severity, or both. Moreover, the effect of a combination of hypertension and diabetes mellitus was conflicting. We aimed to investigate the multiple direct and indirect associations and inspire potential intervention strategies.

Materials and methods

From February 2020 to January 2021, 350 individuals received cognitive tests within 7 days after incident stroke. Cognitive tests were performed using the Chinese version of the Mini-Mental State Exam

SUBMITTER: Hua J 

PROVIDER: S-EPMC9389173 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature