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Prediction of pre-eclampsia by using radiomics nomogram from gestational hypertension patients.


ABSTRACT:

Background

Pre-eclampsia (PE) is the main cause of death in maternal and prenatal morbidity. No effective clinical tools could be used for the prediction of PE. A radiomics nomogram based on diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps was established to predict PE from gestational hypertension (GH).

Materials and methods

A total of 138 patients with hypertensive disorders of pregnancy were continuously enrolled in the study prospectively, namely, 58 patients with PE and 80 patients with GH. The patients were randomly divided into a training cohort (n = 97) and a test cohort (n = 41). Radiomics features were extracted from DWI and ADC maps. The radiomics signature was constructed using a least absolute shrinkage and selection o

SUBMITTER: Liu XF 

PROVIDER: S-EPMC9389207 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature